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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
17.5 DPC

16 matching records from 16 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Ihh  Indian hedgehog  
Results  Reference
1J:85994 Aszodi A, Hunziker EB, Brakebusch C, Fassler R, Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. Genes Dev. 2003 Oct 1;17(19):2465-79
1J:67277 Chung UI, Schipani E, McMahon AP, Kronenberg HM, Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest. 2001 Feb;107(3):295-304
1J:98427 Day TF, Guo X, Garrett-Beal L, Yang Y, Wnt/beta-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis. Dev Cell. 2005 May;8(5):739-50
1*J:138379 Gu S, Wei N, Yu L, Fei J, Chen Y, Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42
1J:131986 Han M, Yang X, Lee J, Allan CH, Muneoka K, Development and regeneration of the neonatal digit tip in mice. Dev Biol. 2008 Mar 1;315(1):125-35
1J:171670 Hojyo S, Fukada T, Shimoda S, Ohashi W, Bin BH, Koseki H, Hirano T, The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth. PLoS One. 2011;6(3):e18059
1J:253972 Hwang SH, White KA, Somatilaka BN, Shelton JM, Richardson JA, Mukhopadhyay S, The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner. Development. 2018 Jan 8;145(1):dev154054
1J:223126 Inman KE, Purcell P, Kume T, Trainor PA, Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia. PLoS Genet. 2013;9(12):e1003949
1*J:53540 Kim IS, Otto F, Zabel B, Mundlos S, Regulation of chondrocyte differentiation by Cbfa1. Mech Dev. 1999 Feb;80(2):159-70
1J:169421 Klopocki E, Lohan S, Brancati F, Koll R, Brehm A, Seemann P, Dathe K, Stricker S, Hecht J, Bosse K, Betz RC, Garaci FG, Dallapiccola B, Jain M, Muenke M, Ng VC, Chan W, Chan D, Mundlos S, Copy-number variations involving the IHH locus are associated with syndactyly and craniosynostosis. Am J Hum Genet. 2011 Jan 7;88(1):70-5
1J:77683 Kobayashi T, Chung UI, Schipani E, Starbuck M, Karsenty G, Katagiri T, Goad DL, Lanske B, Kronenberg HM, PTHrP and Indian hedgehog control differentiation of growth plate chondrocytes at multiple steps. Development. 2002 Jun;129(12):2977-86
1J:161784 Lyashenko N, Weissenbock M, Sharir A, Erben RG, Minami Y, Hartmann C, Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded. Dev Dyn. 2010 Aug;239(8):2266-77
1*J:93152 Maclean HE, Kronenberg HM, Expression of Stra13 during mouse endochondral bone development. Gene Expr Patterns. 2004 Oct;4(6):633-6
1J:100378 MacLean HE, Kronenberg HM, Localization of Indian hedgehog and PTH/PTHrP receptor expression in relation to chondrocyte proliferation during mouse bone development. Dev Growth Differ. 2005 Feb;47(2):59-63
1J:88817 Smits P, Dy P, Mitra S, Lefebvre V, Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate. J Cell Biol. 2004 Mar 1;164(5):747-58
1J:138616 Yang X, Harkins LK, Zubanova O, Harrington A, Kovalenko D, Nadeau RJ, Chen PY, Toher JL, Lindner V, Liaw L, Friesel R, Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia. Dev Biol. 2008 Sep 1;321(1):64-76

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory